MyHealthspan
Hereditary Risk DNA Test (163 Genes)
Hereditary Risk DNA Test (163 Genes)
Regular price
$549.00
Regular price
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$549.00
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A 163-gene hereditary risk panel screening for actionable cancer and cardiac variants, with a certified genetic counselor and Longevity Coach included to ensure you understand exactly what your results mean. $549 CAD.
How It Works
1
Order online
Complete your purchase and your at-home nasal swab collection kit ships directly to your door within a few business days.
2
Receive your kit and provide your sample
Follow the clear step-by-step instructions to collect your nasal swab sample. The process takes under five minutes and requires no clinic visit.
3
Mail your sample back for 163-gene analysis
Use the prepaid return envelope to send your sample to our certified laboratory. Your DNA undergoes a comprehensive 163-gene hereditary risk analysis. Results are ready in 3 to 4 weeks.
4
1-hour genetic counselor session and 1-hour Longevity Coach session
A certified genetic counselor reviews your results with you in a dedicated 1-hour session. A separate 1-hour Longevity Coach consultation then translates findings into a personalized prevention and screening plan.
What You'll Learn
- Whether you carry actionable hereditary variants linked to cancer or cardiac conditions across 163 clinically significant genes
- How your genetic risk profile should shape your screening schedule, including whether earlier or more frequent screening is warranted for specific cancers or cardiac conditions
- Specific evidence-based interventions that meaningfully reduce risk even when hereditary variants are present, reviewed by your genetic counselor
- A complete genetic risk summary that integrates into your MyHealthspan Longevity Score and informs all future health decisions
What's Included
- At-home nasal swab collection kit, shipped to your door
- 163-gene hereditary DNA analysis performed at a certified laboratory
- 1-hour certified genetic counselor consultation to review your results
- 1-hour Longevity Coach consultation to build your personalized prevention plan
- Personalized Cancer Longevity Guide with tailored screening and lifestyle recommendations
- Updated MyHealthspan Longevity Score with hereditary genetic insights
- Results delivered in the MyHealthspan app
Who This Test Is For
This test is for someone who has a family history of cancer or early-onset heart disease and wants to know definitively whether they carry hereditary risk variants that change their prevention and screening strategy. It is equally chosen by proactive individuals who want to establish a complete genetic baseline before any symptoms arise, because they understand that knowing your hereditary risk is one of the most powerful forms of prevention available. Knowing a variant is present shapes every downstream decision — from how often you screen, to which lifestyle interventions are most urgent, to conversations you have with your specialists. The genetic counselor and Longevity Coach combination means you will not be left to interpret complex or potentially alarming results alone. This test is for people who believe that the best time to act on genetic information is before it becomes clinically urgent.
What We Analyze
This panel screens 163 genes for hereditary variants associated with actionable cancer and cardiac risk. Key genes and conditions covered include:
Hereditary Breast and Ovarian Cancer
BRCA1, BRCA2, PALB2, RAD51C, RAD51D — the most clinically significant hereditary breast and ovarian cancer genes
Hereditary Colorectal Cancer
Lynch syndrome genes (MLH1, MSH2, MSH6, PMS2, EPCAM) associated with hereditary colorectal and endometrial cancer risk
Additional Cancer Risk Genes
ATM, CHEK2, TP53 (Li-Fraumeni syndrome), and 100+ additional genes across hereditary cancer syndromes
Hereditary Cardiac Conditions
KCNQ1, SCN5A, MYBPC3, LMNA, and related genes associated with hereditary arrhythmia, cardiomyopathy, and sudden cardiac risk
Doctor-founded by Dr. Zia Poonja, practicing oncologist. Every protocol is clinically designed.
PHIPA + PIPEDA compliant. Your health data stays in Canada, encrypted and private.
HSA/FSA eligible. Use your health spending account.
5-star rated on Trustpilot. Trusted by thousands of Canadians.
"Through the initial testing, we uncovered key vitamin deficiencies, identified actionable ways to improve my heart health markers, and most significantly, discovered I have hypercalcaemia. I'm now on the waitlist for surgery."Safana V., MyHealthspan member
Frequently Asked Questions
Is a positive result the same as a diagnosis?+
No. A positive result means you carry a hereditary variant associated with increased risk for a particular condition. It is not a diagnosis of cancer or heart disease, and it does not mean you will develop that condition. Many people who carry BRCA1, BRCA2, or Lynch syndrome variants live their full lives without developing the associated cancers, particularly when they follow enhanced surveillance and risk-reduction protocols. What a positive result does is give you highly actionable information that allows you to make smarter decisions about screening frequency, lifestyle, and in some cases, preventive medical interventions. Your certified genetic counselor will explain exactly what your result means and what the evidence-based options are for your specific variant.
What genes are included in the 163-gene panel?+
The panel includes all major clinically actionable hereditary cancer genes including BRCA1, BRCA2, PALB2, ATM, CHEK2, RAD51C, RAD51D, TP53, and the Lynch syndrome genes MLH1, MSH2, MSH6, PMS2, and EPCAM. It also includes hereditary cardiac genes associated with arrhythmia syndromes and cardiomyopathies, including KCNQ1, SCN5A, MYBPC3, and LMNA. The remaining genes cover a broad range of additional hereditary cancer syndromes including hereditary diffuse gastric cancer, pancreatic cancer predisposition, and melanoma risk genes. A full gene list is available on request and will be provided in your results report.
Is genetic counseling included?+
Yes. A dedicated 1-hour session with a certified genetic counselor is included with this test, and it is not optional — it is a core component of the product. A 163-gene hereditary panel can return complex results including pathogenic variants, variants of uncertain significance, and findings with nuanced clinical implications. A certified genetic counselor is trained to communicate these results clearly, explain what they mean for your health and for your family members, and help you understand what your options are. You will not receive a result of this magnitude without expert support to contextualize it.
How is this different from 23andMe or AncestryDNA?+
Consumer genetics tests like 23andMe screen a limited set of variants using genotyping arrays and typically cover only a small fraction of clinically significant variants even within genes like BRCA1 and BRCA2. A negative result on 23andMe does not rule out a hereditary variant. This panel uses next-generation sequencing (NGS) to comprehensively analyze all coding regions of 163 clinically significant genes, providing a far more complete and clinically reliable assessment. It is also accompanied by certified genetic counseling, which consumer tests do not provide. If you have had a consumer genetics test, those results cannot substitute for a clinical-grade panel like this one.
What happens if a pathogenic variant is found?+
Your genetic counselor session is specifically built for this scenario. Your counselor will explain what the pathogenic variant means for your specific risk profile, which cancers or cardiac conditions are associated with it and at what approximate magnitude, what the evidence-based surveillance and risk-reduction options are, and whether your immediate family members should consider testing. Your Longevity Coach session then translates that information into a concrete prevention and screening plan integrated with your broader health picture. You will leave both sessions with a clear understanding of your situation and a concrete path forward. Finding a pathogenic variant is not the end of the story — it is the beginning of a much more targeted and effective prevention strategy.
Already a MyHealthspan member? Check your membership tier — this test may already be included. View membership options →
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